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Lab Anim ; 55(2): 177-180, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33045909

RESUMO

Pigs are used to model humans in gastrointestinal (GI) studies because of their comparable size, physiology and behaviour: both are monogastric omnivores. A porcine surgical model for testing novel, tethered ultrasound capsule endoscopes (USCE) requires a clean, motile small intestine. Recommendations for human GI tract preparation before the mechanically similar process of video capsule endoscopy describe using oral purgatives, while high-carbohydrate drinks are recommended before colorectal surgery. Reports of the GI preparation of pigs exist but lack technical details, that is, administration, efficacy and side effects. This report details feeding a high-energy liquid diet to 11 female pigs undergoing surgery and USCE which was readily accepted and easily administered, and which produced a clean, motile small intestine and caused no detectable physiological/behavioural abnormalities.


Assuntos
Criação de Animais Domésticos/métodos , Cápsulas Endoscópicas/estatística & dados numéricos , Endoscopia por Cápsula/estatística & dados numéricos , Dieta , Sus scrofa/fisiologia , Animais , Feminino , Intestino Delgado/fisiologia , Modelos Animais , Sus scrofa/cirurgia
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